I think Mitchell girls have a good shot to come out of the bottom half of the bracket and be in the regional finals, it's between them and Alleghany, no one else has a chance. I do think Mitchell and Alleghany have good teams but they will not be battle tested the way the winner of the top half of the bracket is.
As for the boys Andrews has plenty of talent but it's starting to look like they peaked earlier in the season when they were playing like a top 15 or so team in 1A. If the good version of Andrews shows up for the playoffs they will make it to a 3rd round matchup with Lincoln Charter, if the team that scuffled through the end of the regular season heads to Mitchell it will probably be a short playoff stay for Andrews.